Dr Walter Mertz discovered that this "active" chromium was complexed with several amino acids and the B-vitamin niacin and called this chromium complex: "Glucose Tolerance Factor" or "GTF."
Dr. Mertz concluded that niacin was the key to chromium's biological activity. Neither niacin by itself nor the common chromium picolinate complex had any significant effect on glucose metabolism.
In the early 1970's, Dr. Mertz concluded that the niacin-bound chromium, called "polynicotinate" or "nicotinate" was the biologically active form of chromium that potentiates insulin's action in the body.
Chromium GTF Polynicotinate promotes optimal regulation of cholesterol, as well as glucose and fat metabolism. Chromium GTF Polynicotinate is a bioavailable source of chromium (better than chromium picolinate) for those needing supplemental chromium.
A 3-month double-blind study of 122 moderately overweight individuals attempting to lose weight found that 400 mcg of chromium daily resulted in an average loss of 6.2 pounds of body fat, as opposed to 3.4 pounds in the placebo group.
There was no loss of lean body mass.2 These results suggest that chromium can help you lose body fat without losing muscle. It may work by helping the body process its insulin more effectively.
Reference :
Kaats GR, Blum K, Pullin D, et al. A randomized, double-masked, placebo-controlled study of the effects of chromium picolinate supplementation on body composition: a replication and extension of a previous study. Curr Ther Res. 1998;59:379-388.
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